Expert OpinionPrice Target UpdateSector Analysis

Smart Money Is Betting Big In PFE Options

Benzingaβ€’December 05, 2025 at 5:01 PMβ€’Full Content
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Detected Companies & Sentiment

Pfizer Inc.
"bullish momentum"
9

Gist

Major institutional investors are showing strong bearish sentiment in Pfizer's options, with significant put activity and a majority of trades indicating downside expectations.

LLM Summary

Unusual options activity in Pfizer (PFE) reveals that 65% of traders are bearish, with $543K in put trades and $775K in call trades. Institutional interest suggests a potential price range of $20–$35, while analysts offer mixed viewsβ€”Citigroup downgraded to Neutral, and Guggenheim maintains a Buy with a $35 target.

Full Article Content

Financial giants have made a conspicuous bearish move on Pfizer. Our analysis of options history for Pfizer (NYSE: PFE) revealed 20 unusual trades.

Delving into the details, we found 35% of traders were bullish, while 65% showed bearish tendencies. Out of all the trades we spotted, 2 were puts, with a value of $543,015, and 18 were calls, valued at $775,183.

Projected Price Targets

Analyzing the Volume and Open Interest in these contracts, it seems that the big players have been eyeing a price window from $20.0 to $35.0 for Pfizer during the past quarter.

Insights into Volume & Open Interest

Looking at the volume and open interest is an insightful way to conduct due diligence on a stock.

This data can help you track the liquidity and interest for Pfizer's options for a given strike price.

Below, we can observe the evolution of the volume and open interest of calls and puts, respectively, for all of Pfizer's whale activity within a strike price range from $20.0 to $35.0 in the last 30 days.

Pfizer Call and Put Volume: 30-Day Overview

!Options Call Chart

Significant Options Trades Detected:

SymbolPUT/CALLTrade TypeSentimentExp. DateAskBidPriceStrike PriceTotal Trade PriceOpen InterestVolumePFEPUTTRADEBULLISH02/20/26$0.36$0.32$0.33$23.00$495.0K2.8K15.0KPFECALLSWEEPBEARISH12/26/25$1.1$1.04$1.04$25.00$104.0K1.3K1.0KPFECALLTRADEBULLISH04/17/26$2.1$1.97$2.05$25.00$80.9K3.0K451PFECALLTRADEBEARISH04/17/26$2.03$1.98$1.99$25.00$79.0K3.0K850PFECALLSWEEPBULLISH12/19/25$1.15$1.13$1.15$25.00$62.5K38.7K2.1K

About Pfizer

Pfizer is one of the world's largest pharmaceutical firms, with annual sales of roughly $60 billion. While it historically sold many types of healthcare products and chemicals, now prescription drugs and vaccines account for the majority of sales. Top sellers include pneumococcal vaccine Prevnar 13, cancer drug Ibrance, and cardiovascular treatment Eliquis. Pfizer sells these products globally, with international sales representing 40% of total sales. Within international sales, emerging markets are a major contributor.

Having examined the options trading patterns of Pfizer, our attention now turns directly to the company. This shift allows us to delve into its present market position and performance

Present Market Standing of Pfizer

- Currently trading with a volume of 13,029,040, the PFE's price is up by 0.82%, now at $25.91.

- RSI readings suggest the stock is currently may be approaching overbought.

- Anticipated earnings release is in 60 days.

Expert Opinions on Pfizer

A total of 2 professional analysts have given their take on this stock in the last 30 days, setting an average price target of $30.5.

Unusual Options Activity Detected: Smart Money on the Move

\\* Reflecting concerns, an analyst from Citigroup lowers its rating to Neutral with a new price target of $26.

\\* An analyst from Guggenheim has decided to maintain their Buy rating on Pfizer, which currently sits at a price target of $35.

Metadata

Author:
Benzinga Insights
Image URL:
https://cdn.benzinga.com/files/imagecache/250x187xUP/images/story/2025/11/06/movers_4.jpg
Tickers:
PFE
Updated At:
December 05, 2025 at 1:01 PM
Benzinga Channels:
Options, Markets
Benzinga Tags:
BZI-UOA
Teaser:
Benzinga Stocks:
PFE (NYSE)
Benzinga Article ID:
49235695